Description

Ethyl 1-Benzyl-3-(Dibenzylcarbamoyl)-5-Oxopyrrolidine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex pyrrolidine-based structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development pipelines targeting complex therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, custom synthesis providers, and manufacturers of fine chemicals seeking to develop next-generation drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of complex drug molecules, especially those containing pyrrolidine or proline-like scaffolds.
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities (NCEs) for various therapeutic targets, enabling structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and APIs under cGMP conditions.
• Protease Inhibitor Development: A potential precursor in the synthesis of inhibitors targeting specific enzymes, given its carbamoyl and ester functional groups.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental organic chemistry research and methodology development.

Basic Information

Product Name	Ethyl 1-Benzyl-3-(Dibenzylcarbamoyl)-5-Oxopyrrolidine-3-Carboxylate
CAS No.	162686-37-5
Molecular Formula	C29H30N2O4
Molecular Weight	470.56 g/mol
Synonyms	1-Benzyl-3-(dibenzylcarbamoyl)-5-oxopyrrolidine-3-carboxylic acid ethyl ester; Ethyl 1-benzyl-3-[(dibenzylamino)carbonyl]-5-oxo-3-pyrrolidinecarboxylate; 3-Pyrrolidinecarboxylic acid, 1-benzyl-3-[(dibenzylamino)carbonyl]-5-oxo-, ethyl ester; 1-Benzyl-3-(N,N-dibenzylcarbamoyl)-5-oxopyrrolidine-3-carboxylate ethyl ester; 162686-37-5; UNII-7R9C8T8V5H
EINECS	Contact for details

Quality Control

Our Ethyl 1-Benzyl-3-(Dibenzylcarbamoyl)-5-Oxopyrrolidine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive compound.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.