Description

2-Amino-3,3,3-trifluoro-1-propanol is a versatile fluorinated amino alcohol building block of significant interest in advanced chemical synthesis. Its unique structure, combining a trifluoromethyl group with both amino and hydroxyl functionalities, makes it a critical intermediate for introducing fluorine atoms into target molecules, thereby enhancing their metabolic stability, lipophilicity, and binding affinity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in materials science for creating specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, including protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the trifluoromethyl group improves biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a fluorinated component in the synthesis of liquid crystals for display technologies, improving dielectric anisotropy and stability.
• Polymer Modification: Employed to introduce fluorine into polymer backbones or side chains, enhancing chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: A valuable chiral synthon for asymmetric synthesis and the preparation of complex fluorinated organic molecules in research and development.
• Coordination Chemistry: Acts as a ligand for metal complexes used in catalysis or material science applications.

Basic Information

Product Name	2-Amino-3,3,3-trifluoro-1-propanol
CAS No.	162684-85-7
Molecular Formula	C₃H₆F₃NO
Molecular Weight	129.08 g/mol
Synonyms	3-Amino-1,1,1-trifluoro-2-propanol; 1,1,1-Trifluoro-3-amino-2-propanol; 3,3,3-Trifluoro-2-hydroxypropylamine; 2-Hydroxy-3,3,3-trifluoropropylamine; 3-Amino-1,1,1-trifluoropropan-2-ol; 2-Propanol, 2-amino-3,3,3-trifluoro-; TFAP
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3,3,3-trifluoro-1-propanol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and oxidizing agents. Due to its functional groups, the material should be handled in a controlled environment to minimize moisture uptake and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.