Description

5-o-(1-Methoxy-1-Methylethyl)-2,3-o-(1-Methylethylidene)-D-Ribonic Acid γ-Lactone is a high-purity, advanced pharmaceutical intermediate characterized by its protected ribonic acid lactone structure. This compound is critical for ensuring precise stereochemistry and functional group integrity in complex synthetic pathways. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of nucleoside analogs and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Chiral Synthesis: Serves as a chiral precursor or auxiliary in asymmetric synthesis for producing enantiomerically pure compounds.
• Glycochemistry Research: Used in the study and synthesis of complex carbohydrates, glycoconjugates, and glycomimetics.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals requiring protected sugar derivatives.
• Process Development: Utilized in route scouting and scale-up optimization for API (Active Pharmaceutical Ingredient) manufacturing.
• Academic & Industrial R&D: A valuable reagent for exploring new chemical entities and reaction methodologies in medicinal chemistry.

Basic Information

Product Name	5-o-(1-Methoxy-1-Methylethyl)-2,3-o-(1-Methylethylidene)-D-Ribonic Acid γ-Lactone
CAS No.	162635-53-2
Molecular Formula	C12H20O6
Molecular Weight	260.28 g/mol
Synonyms	2,3-O-Isopropylidene-5-O-(1-methoxy-1-methylethyl)-D-ribono-1,4-lactone; D-Ribonic acid, 5-O-(1-methoxy-1-methylethyl)-2,3-O-(1-methylethylidene)-, γ-lactone; 5-O-(1-Methoxy-1-methylethyl)-2,3-O-isopropylidene-D-ribonolactone; Protected D-Ribonolactone; Isopropylidene Ribonolactone Derivative
EINECS	Contact for details

Quality Control

Every batch of 5-o-(1-Methoxy-1-Methylethyl)-2,3-o-(1-Methylethylidene)-D-Ribonic Acid γ-Lactone is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.