Description

2(3H)-Furanone, 4-Ethynyldihydro-3,5-Dimethyl-, [3R-(3Alpha,4Alpha,5Alpha)]- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring a fused furanone ring with an ethynyl substituent, makes it a versatile precursor for constructing complex, biologically active molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides with specific stereochemical requirements.
• Advanced Material Research: Serves as a monomer or precursor in the development of specialized polymers and functional materials.
• Asymmetric Catalysis: Employed as a ligand precursor or a test substrate in the development of new catalytic systems.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and the synthesis of complex natural product analogs.
• Fine Chemical Production: Acts as a building block for the custom synthesis of high-value, low-volume specialty chemicals.

Basic Information

Product Name	2(3H)-Furanone, 4-Ethynyldihydro-3,5-Dimethyl-, [3R-(3Alpha,4Alpha,5Alpha)]- (9Ci)
CAS No.	162612-26-2
Molecular Formula	C9H10O2
Molecular Weight	150.17 g/mol
Synonyms	4-Ethynyldihydro-3,5-dimethyl-2(3H)-furanone, (3R,4R,5R)-; (3R,4R,5R)-4-Ethynyl-3,5-dimethyl-dihydrofuran-2(3H)-one; [3R-(3α,4α,5α)]-4-Ethynyldihydro-3,5-dimethyl-2(3H)-furanone; Chiral 4-ethynyl dihydrofuranone; 3,5-Dimethyl-4-ethynyl-dihydro-2(3H)-furanone; (3R,4R,5R)-3,5-Dimethyl-4-ethynyltetrahydrofuran-2-one
EINECS	Contact for details

Quality Control

Our production of 2(3H)-Furanone, 4-Ethynyldihydro-3,5-Dimethyl-, [3R-(3Alpha,4Alpha,5Alpha)]- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider maintaining the product under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.