Description

Heptamethine Cyanine Dye-1 CAS NO 162411-29-2 is a near-infrared (NIR) fluorescent dye belonging to the cyanine family, characterized by its heptamethine bridge. This compound matters for its exceptional photophysical properties, including high molar absorptivity and fluorescence quantum yield in the NIR region, which is crucial for deep-tissue imaging and minimizing background autofluorescence. It is primarily needed by researchers and manufacturers in the biotechnology, medical diagnostics, and material science sectors for applications such as bioimaging, optical sensing, and the development of photonic devices.

Application

• Bioimaging and Biosensing: Used as a fluorescent probe for in vivo and in vitro imaging, particularly for deep-tissue visualization due to its NIR emission.
• Medical Diagnostics: A key component in the development of diagnostic assays, including fluorescence immunoassays (FLISA) and DNA detection.
• Photodynamic Therapy (PDT): Investigated as a photosensitizer for cancer treatment, leveraging its light absorption to generate reactive oxygen species.
• Optical Data Storage: Employed in the research and development of advanced optical recording materials.
• Laser Dyes: Functions as a gain medium in tunable dye lasers operating in the near-infrared spectrum.
• Non-Linear Optics (NLO): Utilized in research for its potential in optical limiting and frequency conversion applications.
• Polymer and Material Science: Incorporated into polymers and nanoparticles to create functional materials with specific optical properties.

Basic Information

Product Name	Heptamethine Cyanine Dye-1
CAS No.	162411-29-2
Molecular Formula	C29H31IN2O2S2
Molecular Weight	654.59 g/mol
Synonyms	IR-780 iodide; 2-[2-[2-Chloro-3-[(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-1,3,3-trimethyl-3H-indolium iodide; NIR-780; Cy7 dye derivative; Heptamethine indocyanine dye; 1,3,3-Trimethyl-2-[5-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)-1,3-pentadienyl]-3H-indolium iodide
EINECS	Contact for details

Quality Control

Our Heptamethine Cyanine Dye-1 is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment, NMR and MS for structural confirmation, and spectrophotometry to verify key optical properties. We ensure compliance with relevant research and development standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Keep the container in a cool, dry, and well-ventilated place. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Dark green to blue-green powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Absorption Maximum (λmax)	780 ± 5 nm
Emission Maximum (λem)	805 ± 10 nm
Moisture Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.