Description

(S)-Ethyl 2-Azido-2-Phenylethanoate is a high-purity chiral building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional azide and ester groups, which enable versatile transformations, particularly in the synthesis of complex nitrogen-containing molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, serving as a key intermediate for the development of active pharmaceutical ingredients (APIs), peptidomimetics, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the asymmetric synthesis of β-amino acids, α-azido acids, and other nitrogen-heterocycles found in drug candidates.
• Peptide Chemistry: Used in the preparation of non-natural amino acid derivatives and as a precursor for "click chemistry" applications via azide-alkyne cycloaddition (CuAAC).
• Agrochemical Research: Serves as a building block for developing novel chiral ligands and active ingredients with specific biological activity.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialized polymers and functional materials.
• Academic & Process R&D: A valuable reagent for methodological development in asymmetric catalysis and stereoselective synthesis.

Basic Information

Product Name	(S)-Ethyl 2-Azido-2-Phenylethanoate
CAS No.	162402-58-6
Molecular Formula	C10H11N3O2
Molecular Weight	205.21 g/mol
Synonyms	(S)-Ethyl 2-Azido-2-phenylacetate; (S)-Ethyl Azido(phenyl)acetate; (S)-2-Azido-2-phenylacetic Acid Ethyl Ester; Ethyl (S)-2-Azido-2-phenylacetate; (S)-α-Azidophenylacetic Acid Ethyl Ester; L-(-)-Ethyl 2-Azido-2-phenylacetate; (S)-(-)-Ethyl 2-Azido-2-phenylacetate
EINECS	Contact for details

Quality Control

Our (S)-Ethyl 2-Azido-2-Phenylethanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and degradation. Keep away from heat, sparks, and open flame. For long-term storage, consider freezing at -20°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (ee, HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.