Description

Ethyl 2-(Diethoxyphosporyl)-2-Hydroxyacetate is a high-value organophosphorus compound that serves as a versatile synthetic intermediate. This chemical is critical for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it enables the introduction of key phosphonate and α-hydroxy ester functionalities. It is primarily sought after by research and development chemists, process development scientists, and manufacturers in fine chemical synthesis for creating active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those with phosphonate-based bioactivity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, plant growth regulators, and insecticides that require specific phosphonate motifs.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized phosphine ligands used in asymmetric catalysis and metal complexation.
• Material Science Research: Employed in the development of flame retardants, specialty polymers, and functional materials incorporating phosphorus.
• Peptide Mimetics and Prodrugs: Utilized to synthesize phosphonate analogs of amino acids and to create prodrug strategies for improved bioavailability.
• Chemical Biology Probes: Acts as a scaffold for creating activity-based probes and enzyme inhibitors targeting metabolic pathways.

Basic Information

Product Name	Ethyl 2-(Diethoxyphosporyl)-2-Hydroxyacetate
CAS No.	162246-79-9
Molecular Formula	C8H17O6P
Molecular Weight	240.19 g/mol
Synonyms	Ethyl (Diethoxyphosphoryl)(hydroxy)acetate; Diethyl (1-Ethoxy-1-oxo-2-hydroxy-2-oxoethyl)phosphonate; 2-Hydroxy-2-(diethoxyphosphoryl)acetic acid ethyl ester; Ethyl 2-hydroxy-2-(diethoxyphosphoryl)acetate; Acetic acid, 2-(diethoxyphosphinyl)-2-hydroxy-, ethyl ester; Hydroxy(diethoxyphosphoryl)acetic Acid Ethyl Ester; (Diethoxyphosphoryl)(hydroxy)acetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-(Diethoxyphosporyl)-2-Hydroxyacetate is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.