Description

(2-Amino-Benzyl)-Carbamic Acid tert-Butyl Ester is a protected amine derivative, specifically a Boc-protected ortho-aminobenzylamine, serving as a crucial building block in organic synthesis. Its value lies in providing a versatile and reactive aromatic amine handle that is protected from unwanted side reactions, enabling precise molecular construction. This intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing complex drug molecules, particularly those containing ortho-substituted aniline pharmacophores.
• Peptide Mimetics & Conjugate Chemistry: Used in the preparation of non-peptidic scaffolds and linker systems for bioconjugation and targeted drug delivery.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Dye & Pigment Chemistry: Employed in the synthesis of specialized aromatic amines for high-performance colorants and imaging agents.
• Polymer Modification: Used to introduce functional amine groups into polymer backbones for enhanced material properties.

Basic Information

Product Name	(2-Amino-Benzyl)-Carbamic Acid tert-Butyl Ester
CAS No.	162046-50-6
Molecular Formula	C12H18N2O2
Molecular Weight	222.28 g/mol
Synonyms	tert-Butyl N-[(2-aminophenyl)methyl]carbamate; N-Boc-2-aminobenzylamine; 2-(Boc-aminomethyl)aniline; 1-(tert-Butoxycarbonylamino)-2-aminomethylbenzene; Boc-2-ABn; (2-Aminobenzyl)carbamic acid 1,1-dimethylethyl ester; N-(2-Aminobenzyl)carbamic Acid tert-Butyl Ester; 2-(Aminomethyl)phenylcarbamic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our (2-Amino-Benzyl)-Carbamic Acid tert-Butyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.