Description

2-Amino-1,4-Dihydro-4-Phenyl-1,8-Naphthyridine-3-Carboxylic Acid, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate belonging to the naphthyridine class of heterocyclic compounds. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise molecular architecture that enables targeted drug development. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel therapeutic agents, particularly in areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-infective therapies.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold in the multi-step synthesis of complex APIs, leveraging its naphthyridine structure.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical laboratories.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing more complex polycyclic or fused heterocyclic systems.

Basic Information

Product Name	2-Amino-1,4-Dihydro-4-Phenyl-1,8-Naphthyridine-3-Carboxylic Acid, Ethyl Ester
CAS No.	161987-77-5
Molecular Formula	C₁₇H₁₇N₃O₂
Molecular Weight	295.34 g/mol
Synonyms	Ethyl 2-Amino-1,4-dihydro-4-phenyl-1,8-naphthyridine-3-carboxylate; 4-Phenyl-1,8-naphthyridine-3-carboxylic acid, 2-amino-1,4-dihydro-, ethyl ester; 2-Amino-4-phenyl-1,8-naphthyridine-3-ethyl carboxylate; 1,8-Naphthyridine derivative CAS 161987-77-5; 2-Amino-4-phenyl-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Amino-1,4-Dihydro-4-Phenyl-1,8-Naphthyridine-3-Carboxylic Acid, Ethyl Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.