Description

1-Cyclopentene-1-Heptanoic Acid, 3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-5-Oxo-, Methyl Ester is a high-value, protected synthetic intermediate characterized by its cyclopentene core and silyl ether protecting group. This compound matters for its role in enabling complex multi-step organic syntheses, particularly in the construction of intricate molecular architectures where selective manipulation of functional groups is paramount. It is primarily needed by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for the production of novel active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those containing cyclopentane or modified prostanoid ring systems.
• Organic Synthesis Research: Used in academic and industrial R&D for methodology development, including studies on silyl protection/deprotection strategies and carbonyl chemistry.
• Advanced Material Precursor: Serves as a starting material for synthesizing specialized monomers or ligands used in catalyst design and polymer science.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of high-value fine chemicals.
• Prostanoid Analog Synthesis: The structural motif makes it a valuable intermediate for creating analogs of prostaglandins and other biologically active eicosanoids.

Basic Information

Product Name	1-Cyclopentene-1-Heptanoic Acid, 3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-5-Oxo-, Methyl Ester
CAS No.	161978-56-9
Molecular Formula	C19H34O4Si
Molecular Weight	354.56 g/mol
Synonyms	Methyl 3-[(tert-Butyldimethylsilyl)oxy]-5-oxo-1-cyclopentene-1-heptanoate; 3-[(tert-Butyldimethylsilyl)oxy]-5-oxo-1-cyclopentene-1-heptanoic Acid Methyl Ester; TBDMS-protected 5-oxo-1-cyclopentene-1-heptanoate Methyl Ester; Methyl 3-(TBDMS-oxy)-5-oxo-1-cyclopenten-1-ylheptanoate; 161978-56-9; tert-Butyldimethylsilyl 5-oxo-1-cyclopentene-1-heptanoate derivative
EINECS	Contact for details

Quality Control

Our 1-Cyclopentene-1-Heptanoic Acid, 3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-5-Oxo-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to fluoride and strong alkali; ensure it is stored separately from such materials. For long-term storage, consider keeping the container under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.