Description

tert-Butyl (3R)-3-Amino-3-Phenylpropanoate is a chiral β-amino acid ester derivative, serving as a crucial building block in asymmetric synthesis. Its value lies in providing a protected, enantiomerically pure scaffold for constructing complex pharmaceutical intermediates and fine chemicals. This high-purity chiral synthon is essential for research and production in the pharmaceutical industry, particularly for developing active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of various APIs, including potential candidates for neurological and cardiovascular therapies.
• Asymmetric Synthesis: Used in the preparation of enantiomerically pure compounds via reactions like Michael additions or nucleophilic substitutions.
• Peptidomimetics Research: Serves as a constrained β-amino acid analog for designing and synthesizing novel peptide-like molecules with enhanced metabolic stability.
• Catalyst and Ligand Development: Employed in the synthesis of chiral catalysts and ligands for enantioselective transformations.
• Fine Chemical Production: Integral in the multi-step synthesis of complex, high-value specialty chemicals for agrochemical and material science applications.

Basic Information

Product Name	tert-Butyl (3R)-3-Amino-3-Phenylpropanoate
CAS No.	161671-34-7
Molecular Formula	C₁₃H₁₉NO₂
Molecular Weight	221.30 g/mol
Synonyms	(R)-3-Amino-3-phenylpropanoic acid tert-butyl ester; (R)-tert-Butyl 3-amino-3-phenylpropanoate; (3R)-3-Amino-3-phenylpropanoic acid 1,1-dimethylethyl ester; (R)-β-Amino-β-phenylpropionic acid tert-butyl ester; tert-Butyl (R)-3-amino-3-phenylpropionate; (R)-3-Amino-3-phenyl-propionic acid tert-butyl ester; (R)-3-Phenyl-3-aminopropionic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (3R)-3-Amino-3-Phenylpropanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.