Description

1,4-Dioxaspiro[4.4]Non-6-Ene-6-Carboxaldehyde (9Ci) is a specialized spirocyclic aldehyde building block of significant interest in advanced organic synthesis. This compound matters for its unique structural framework, which serves as a versatile precursor for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific stereochemical requirements.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry, including cycloaddition and ring-opening reactions.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex odorants and flavor molecules with spirocyclic backbones.

Basic Information

Product Name	1,4-Dioxaspiro[4.4]Non-6-Ene-6-Carboxaldehyde (9Ci)
CAS No.	161521-90-0
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	6-Formyl-1,4-dioxaspiro[4.4]non-6-ene; 1,4-Dioxaspiro[4.4]non-6-ene-6-carboxaldehyde; 6-Carboxaldehyde-1,4-dioxaspiro[4.4]non-6-ene; Spiro[1,3-dioxolane-2,1'-cyclohex-3'-ene]-4'-carboxaldehyde; 1,4-Dioxaspiro[4.4]non-6-ene-6-carbaldehyde; (6-Oxo-1,4-dioxaspiro[4.4]non-6-en-6-yl)methanol (tautomer); 9CI Index Name
EINECS	Contact for details

Quality Control

Our 1,4-Dioxaspiro[4.4]Non-6-Ene-6-Carboxaldehyde (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with relevant guidelines for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Allow the container to reach ambient temperature before opening to minimize moisture ingress. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.