Description

3-Cinnolinecarboxylic Acid, 4-Amino-8-Fluoro-, Hydrate is a high-purity, functionalized cinnoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily utilized by research institutions and chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced crop protection agents and herbicides.
• Material Science: Serves as a precursor for the development of specialty chemicals and functional materials with unique electronic or photophysical properties.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening and discovery of bioactive molecules.

Basic Information

Product Name	3-Cinnolinecarboxylic Acid, 4-Amino-8-Fluoro-, Hydrate
CAS No.	161373-45-1
Molecular Formula	C9H6FN3O2 · xH2O
Molecular Weight	207.16 (Anhydrous basis)
Synonyms	4-Amino-8-fluoro-3-cinnolinecarboxylic acid hydrate; 8-Fluoro-4-amino-3-cinnolinecarboxylic acid hydrate; 4-Amino-8-fluorocinnoline-3-carboxylic acid hydrate; 3-Cinnolinecarboxylic acid, 4-amino-8-fluoro-, hydrate; 161373-45-1; 4-Amino-8-fluoro-1,2-benzodiazine-3-carboxylic acid hydrate
EINECS	Contact for details

Quality Control

Our 3-Cinnolinecarboxylic Acid, 4-Amino-8-Fluoro-, Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.