Description

7-Hydroxycoumarinyl-γ-Linolenate is a specialized biochemical conjugate, combining the structural motifs of a coumarin derivative and the essential fatty acid γ-linolenic acid (GLA). This unique molecular architecture makes it a valuable intermediate for research and development in advanced life science applications. It is primarily utilized by researchers and product developers in the pharmaceutical, nutraceutical, and high-value specialty chemical sectors seeking novel bioactive compounds.

Application

• Pharmaceutical Research: Serves as a key synthetic intermediate or a model compound in the development of new therapeutic agents, particularly those targeting inflammatory pathways or with potential anti-proliferative activity.
• Biochemical Probe Development: Used in the design and synthesis of fluorescent or activity-based probes for studying enzyme function, lipid metabolism, and cellular signaling processes due to the coumarin fluorophore.
• Nutraceutical & Cosmetic Ingredient Research: Investigated for its potential bioactive properties, leveraging the combined benefits of coumarin derivatives and γ-linolenic acid in advanced formulation studies.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in HPLC or LC-MS analysis of complex mixtures.
• Organic Synthesis Building Block: Provides a versatile scaffold for medicinal chemists to create libraries of novel derivatives for structure-activity relationship (SAR) studies.

Basic Information

Product Name	7-Hydroxycoumarinyl-γ-Linolenate
CAS No.	161180-12-7
Molecular Formula	C27H38O5
Molecular Weight	442.59 g/mol
Synonyms	7-Hydroxycoumarin γ-linolenate; Umbelliferone γ-linolenic acid ester; GLA-Coumarin ester; 7-[(6Z,9Z,12Z)-Octadeca-6,9,12-trienoyloxy]-2H-chromen-2-one; 7-Hydroxy-2H-1-benzopyran-2-one γ-linolenate; Coumarinyl GLA; γ-Linolenic acid 7-coumarinyl ester
EINECS	Contact for details

Quality Control

Our 7-Hydroxycoumarinyl-γ-Linolenate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider holding under inert atmosphere at lower temperatures (e.g., -20°C) to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.