Description

3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-Phenol is a protected phenol derivative, specifically a tert-butyldimethylsilyl (TBDMS) ether of a phenolic hydroxyl group. This compound is a crucial synthetic intermediate in advanced organic chemistry, valued for its role in protecting sensitive functional groups during multi-step synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of complex molecules, including active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly where selective protection of phenolic OH groups is required.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Organic Synthesis Reagent: Serves as a protected phenol precursor in academic and industrial research laboratories for constructing complex organic architectures.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and performance chemicals where phenol intermediates are needed.
• Material Science Research: Potential monomer or modifier in the development of specialized polymers and advanced materials.

Basic Information

Product Name	3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-Phenol
CAS No.	161006-18-4
Molecular Formula	C12H20O2Si
Molecular Weight	224.37 g/mol
Synonyms	3-[(tert-Butyldimethylsilyl)oxy]phenol; 3-Hydroxyphenyl tert-butyldimethylsilyl ether; 3-(TBDMS-oxy)phenol; Phenol, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 3-(tert-Butyldimethylsiloxy)phenol; 3-TBDMS-Phenol; 3-(O-TBDMS)phenol
EINECS	Contact for details

Quality Control

Our 3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-Phenol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container must be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.