Description

6-Chloro-5-Nitronicotinamide is a high-purity, versatile chemical intermediate characterized by its distinct nitropyridine structure. This compound is critical for facilitating complex molecular transformations in advanced synthetic pathways, offering researchers and manufacturers a reliable building block for creating novel compounds. It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive chloro and nitro groups.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for creating complex heterocyclic compounds and ligands.
• Material Science: Investigated for the development of advanced polymers, dyes, and photoactive materials due to its aromatic nitro functionality.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions, such as Suzuki or Buchwald-Hartwig amination, for carbon-carbon and carbon-nitrogen bond formation.

Basic Information

Product Name	6-Chloro-5-Nitronicotinamide
CAS No.	160906-99-0
Molecular Formula	C6H4ClN3O3
Molecular Weight	201.57 g/mol
Synonyms	5-Nitro-6-chloronicotinamide; 6-Chloro-5-nitropyridine-3-carboxamide; Nicotinamide, 6-chloro-5-nitro-; 3-Pyridinecarboxamide, 6-chloro-5-nitro-; 160906-99-0; 6-Chloro-5-nitro-3-pyridinecarboxamide
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Nitronicotinamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to relevant industry standards, and custom purity grades, including research and pharmaceutical intermediates, are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.