Description

1H-Pyrrole-2-Carboxylicacid,3,4-Difluoro-,Methylester(9Ci) is a fluorinated pyrrole derivative, a high-value specialty chemical building block prized for its unique molecular architecture. This compound is essential for introducing the difluoropyrrole moiety into complex molecules, enabling the fine-tuning of electronic and steric properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-infectives, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atoms and heterocyclic core can enhance biological activity, metabolic stability, and environmental profile.
• Material Science Research: Serves as a precursor for functionalized polymers, organic semiconductors, and liquid crystals, contributing to the development of new electronic and optical materials.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological mechanisms and pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1H-Pyrrole-2-Carboxylicacid,3,4-Difluoro-,Methylester(9Ci)
CAS No.	160561-79-5
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	Methyl 3,4-difluoro-1H-pyrrole-2-carboxylate; 3,4-Difluoro-1H-pyrrole-2-carboxylic acid methyl ester; 1H-Pyrrole-2-carboxylic acid, 3,4-difluoro-, methyl ester; Methyl 3,4-difluoropyrrole-2-carboxylate; 3,4-Difluoropyrrole-2-carboxylic acid methyl ester; 160561-79-5; Methyl 3,4-difluoro-2-pyrrolecarboxylate
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-2-Carboxylicacid,3,4-Difluoro-,Methylester(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.