Description

2-(2-((tert-Butyldiphenylsilyl)Oxy)Ethoxy)Ethanol (Wxpc0004) is a specialized organosilicon-protected polyether derivative, serving as a crucial synthetic intermediate and protecting group reagent. Its primary value lies in enabling complex multi-step organic syntheses, particularly in pharmaceutical and advanced material research, by providing selective protection for hydroxyl functionalities. This compound is essential for R&D chemists and process development scientists working in pharmaceutical manufacturing, fine chemical synthesis, and polymer modification.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly for protecting sensitive hydroxyl groups during multi-step reactions.
• Peptide Synthesis: Used as a protecting group reagent for serine, threonine, or tyrosine residues in solid-phase and solution-phase peptide chemistry.
• Carbohydrate Chemistry: Employed in the selective protection of sugar alcohols and glycosylation reactions for oligosaccharide synthesis.
• Polymer & Material Science: Serves as a functional monomer or chain transfer agent in the synthesis of specialty polyethers and silicone-based polymers.
• Chemical Crosslinking Agent: Utilized in the development of crosslinked networks for hydrogels, resins, and advanced coatings.
• Ligand & Catalyst Synthesis: Intermediate for preparing sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-(2-((tert-Butyldiphenylsilyl)Oxy)Ethoxy)Ethanol (Wxpc0004)
CAS No.	160052-24-4
Molecular Formula	C20H28O3Si
Molecular Weight	344.52 g/mol
Synonyms	2-[2-(tert-Butyldiphenylsilyloxy)ethoxy]ethanol; 2-(2-(tert-Butyldiphenylsilyloxy)ethoxy)ethan-1-ol; TBDPSEEG; tert-Butyldiphenylsilyl-protected diethylene glycol; (2-(2-Hydroxyethoxy)ethoxy)(tert-butyl)diphenylsilane; Ethanol, 2-[2-[(1,1-dimethylethyl)diphenylsilyl]oxy]ethoxy]-; Wxpc0004; TBDPS-O-PEG2-OH
EINECS	Contact for details

Quality Control

Our 2-(2-((tert-Butyldiphenylsilyl)Oxy)Ethoxy)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.