Description

4-(4-Bromo-Phenyl)-3-Oxo-Butyric Acid Ethyl Ester is a high-purity organic intermediate of significant importance in advanced chemical synthesis. This compound matters for its role as a versatile building block in the production of complex pharmaceutical molecules and fine chemicals. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in creating new active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with aryl ketone or β-keto ester backbones.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or building block for the development of advanced polymers and organic electronic materials.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for complex organic transformations, including Claisen condensations and Michael additions.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Fine Chemical Production: Acts as an intermediate for dyes, pigments, and other high-value specialty chemicals.

Basic Information

Item	Details
Product Name	4-(4-Bromo-Phenyl)-3-Oxo-Butyric Acid Ethyl Ester
CAS No.	160010-18-4
Molecular Formula	C12H13BrO3
Molecular Weight	285.14 g/mol
Synonyms	Ethyl 4-(4-Bromophenyl)-3-oxobutanoate; Ethyl 4-(p-Bromophenyl)-3-oxobutyrate; 3-Oxo-4-(4-bromophenyl)butyric Acid Ethyl Ester; 4-(4-Bromophenyl)acetoacetic Acid Ethyl Ester; p-Bromophenacyl Acetoacetate; 4-Bromophenyl Ethyl Acetoacetate; 160010-18-4
EINECS	Contact for details

Quality Control

Our 4-(4-Bromo-Phenyl)-3-Oxo-Butyric Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, assay, and impurity profiles to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.