Description

Racemic cis-tert-Butyl Hexahydropyrrolo[3,4-B][1,4]Oxazine-6(2H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate crucial for modern synthetic chemistry. This compound serves as a key chiral building block in the development of complex active pharmaceutical ingredients (APIs), enabling the synthesis of molecules with specific stereochemical configurations. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in the areas of central nervous system (CNS) agents and other specialized drug candidates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to construct molecules with defined three-dimensional structures.
• Medicinal Chemistry R&D: Employed in research laboratories for the discovery and optimization of new drug candidates, particularly in neuroscience.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for drug manufacturing.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for the production of client-specific compounds.
• Academic Research: Used in university and institutional research focused on novel heterocyclic chemistry and synthetic methodology development.

Basic Information

Product Name	Racemic cis-tert-Butyl Hexahydropyrrolo[3,4-B][1,4]Oxazine-6(2H)-Carboxylate
CAS No.	159991-15-8
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	tert-Butyl (3aR,7aS)-hexahydro-1H-pyrrolo[3,4-b][1,4]oxazine-6(2H)-carboxylate (cis-); (3aR,7aS)-rel-2-(1,1-Dimethylethyl) Hexahydro-1H-pyrrolo[3,4-b][1,4]oxazine-6-carboxylate; cis-tert-Butyl Hexahydropyrrolo[3,4-b][1,4]oxazine-6-carboxylate; Hexahydro-1H-pyrrolo[3,4-b][1,4]oxazine-6(2H)-carboxylic Acid, 1,1-Dimethylethyl Ester, cis-; BOC-protected Hexahydropyrrolooxazine; BOC-Hexahydropyrrolooxazine; (cis)-tert-Butyl Hexahydro-2H-pyrrolo[3,4-b][1,4]oxazine-6(7H)-carboxylate
EINECS	Contact for details

Quality Control

Our Racemic cis-tert-Butyl Hexahydropyrrolo[3,4-B][1,4]Oxazine-6(2H)-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) standards where applicable, and our quality protocols are designed to meet the stringent requirements of global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Related Substances (HPLC)	Individual unknown impurity ≤ 0.5% Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.