Description

5-(Chloromethyl)-2-(2,2,2-Trifluoroethoxy)Pyridine is a high-value, multi-functional chemical intermediate designed for advanced synthesis. This compound is critical for introducing both a reactive chloromethyl group and a trifluoroethoxy moiety into complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the construction of novel active ingredients. Its unique structure makes it an essential building block for creating compounds with enhanced biological activity and specific physicochemical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoroethoxy group can improve metabolic stability and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in organometallic chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic properties.
• Custom Synthesis and Contract Manufacturing: A crucial starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-(Chloromethyl)-2-(2,2,2-Trifluoroethoxy)Pyridine
CAS No.	159981-21-2
Molecular Formula	C8H7ClF3NO
Molecular Weight	225.60 g/mol
Synonyms	2-(2,2,2-Trifluoroethoxy)-5-(chloromethyl)pyridine; 5-(Chloromethyl)-2-(2,2,2-trifluoroethoxy)pyridine; Pyridine, 5-(chloromethyl)-2-(2,2,2-trifluoroethoxy)-; 159981-21-2; 2-(Trifluoroethoxy)-5-chloromethylpyridine
EINECS	Contact for details

Quality Control

Every batch of 5-(Chloromethyl)-2-(2,2,2-Trifluoroethoxy)Pyridine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.