Description

1-(Azidomethyl)-4-Fluorobenzene (Saltdata: Free) is a versatile aromatic azide building block used in advanced organic synthesis. This compound is valued for its ability to participate in click chemistry reactions, particularly the copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling efficient and selective molecular assembly. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients, polymers, and probes. The high purity and consistent quality of this intermediate are critical for ensuring reliable reaction outcomes in complex synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially in medicinal chemistry programs utilizing bioorthogonal chemistry.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the azide group enables the introduction of specific functional moieties.
• Polymer & Materials Science: Serves as a functional monomer or cross-linking agent in the creation of advanced polymers, hydrogels, and smart materials via click chemistry.
• Bioconjugation & Probe Development: Essential for labeling biomolecules (proteins, antibodies, nucleic acids) with fluorescent dyes or other tags for diagnostic and research applications.
• Chemical Biology Research: Employed as a tool compound to study biological processes and for activity-based protein profiling (ABPP).
• Ligand & Catalyst Development: Used to synthesize novel ligands and organometallic complexes with potential catalytic activity.

Basic Information

Product Name	1-(Azidomethyl)-4-Fluorobenzene (Saltdata: Free)
CAS No.	159979-96-1
Molecular Formula	C7H6FN3
Molecular Weight	151.14 g/mol
Synonyms	4-Fluorobenzyl Azide; (4-Fluorophenyl)methyl Azide; p-Fluorobenzyl Azide; Azidomethyl-4-fluorobenzene; 1-(Azidomethyl)-4-fluorobenzene; 4-Fluorobenzylazide; α-Azido-4-fluorotoluene; 4-Fluoro-α-azidotoluene
EINECS	Contact for details

Quality Control

Our 1-(Azidomethyl)-4-Fluorobenzene is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our customers in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers must be kept sealed when not in use and stored away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.