Description

Methyl(R)-n-Boc-3-Aminobutyrate CAS NO 159877-47-1 is a high-purity chiral building block and protected amino acid ester, essential for the synthesis of complex pharmaceutical intermediates and fine chemicals. Its value lies in providing a stereochemically defined, readily functionalizable scaffold that is critical for constructing molecules with specific biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing new active ingredients and specialty products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and metabolic diseases.
• Peptidomimetics Research: Used to introduce the (R)-3-aminobutyric acid moiety into peptide backbones to modify stability, bioavailability, and receptor binding.
• Asymmetric Synthesis: Serves as a starting material or chiral auxiliary in catalytic asymmetric reactions to construct complex molecular architectures.
• Agrochemical Development: Employed in the research and production of chiral herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Utilized for synthesizing chiral ligands and organocatalysts used in enantioselective transformations.
• Custom Chemical Synthesis: A versatile building block for contract research and manufacturing organizations (CROs/CMOs) producing custom fine chemicals.

Basic Information

Product Name	Methyl(R)-n-Boc-3-Aminobutyrate
CAS No.	159877-47-1
Molecular Formula	C10H19NO4
Molecular Weight	217.26 g/mol
Synonyms	(R)-Methyl 3-((tert-Butoxycarbonyl)amino)butanoate; (R)-3-[(tert-Butoxycarbonyl)amino]butyric Acid Methyl Ester; Methyl (3R)-3-[(tert-Butoxycarbonyl)amino]butanoate; (R)-Boc-3-Aminobutyric Acid Methyl Ester; Boc-β3-hAla-OMe; (R)-Boc-β3-HomAlanine Methyl Ester; (R)-Boc-Abu-OMe; Methyl (R)-3-(Boc-amino)butyrate
EINECS	Contact for details

Quality Control

Our Methyl(R)-n-Boc-3-Aminobutyrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with stringent industry standards for advanced synthetic intermediates. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Enantiomeric Excess (Chiral HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.