Description

Cyclopropanecarboxylic Acid, 1-Amino-, 1,1-Dimethylethyl Ester is a high-purity, protected amino acid derivative featuring a cyclopropane ring, a key structural motif in advanced organic synthesis. This compound is valued for its role as a critical chiral building block in the development of novel active pharmaceutical ingredients (APIs) and complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, process development, and the synthesis of peptide mimetics and other constrained analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Peptidomimetics & Constrained Peptide Synthesis: Used to introduce the rigid, three-membered cyclopropane ring into peptide backbones to enhance metabolic stability and conformational control.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides with unique modes of action.
• Asymmetric Synthesis: Employed in catalytic asymmetric reactions to construct complex molecules with high enantiomeric purity.
• Material Science: Potential monomer or precursor for specialty polymers and advanced materials with tailored properties.
• Chemical Biology & Proteomics: Useful as a probe or labeling agent for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Amino-, 1,1-Dimethylethyl Ester
CAS No.	159871-51-9
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	1-Aminocyclopropanecarboxylic acid tert-butyl ester; tert-Butyl 1-aminocyclopropanecarboxylate; Boc-1-Amino-1-cyclopropanecarboxylic acid; 1-(tert-Butoxycarbonyl)aminocyclopropanecarboxylic acid; ACCA-OtBu; 1-Boc-amino-1-cyclopropanecarboxylic acid; 1-N-Boc-1-aminocyclopropanecarboxylic acid; (1-Aminocyclopropyl)carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-Amino-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.