Description

Methyl 4-Fluoro-5-Methoxy-2-Nitrobenzoate is a high-purity, multi-functional aromatic ester building block designed for advanced chemical synthesis. This compound is valued for its unique substitution pattern, which provides a versatile chemical handle for constructing complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced intermediates, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and anti-cancer compounds.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine and nitro groups for enhanced biological activity and stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Synthesis: Acts as an intermediate for creating complex aromatic structures used in high-performance dyes and organic pigments.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development, catalysis studies, and exploring new chemical spaces.
• Custom Synthesis Starting Material: Provides a reliable and well-defined starting point for custom synthesis and scale-up projects requiring specific aromatic substitution patterns.

Basic Information

Product Name	Methyl 4-Fluoro-5-Methoxy-2-Nitrobenzoate
CAS No.	159768-50-0
Molecular Formula	C9H8FNO5
Molecular Weight	229.16 g/mol
Synonyms	Benzoic acid, 4-fluoro-5-methoxy-2-nitro-, methyl ester; Methyl 4-fluoro-5-methoxy-2-nitrobenzoate; 4-Fluoro-5-methoxy-2-nitrobenzoic acid methyl ester; 2-Nitro-4-fluoro-5-methoxybenzoic acid methyl ester; Methyl 2-nitro-4-fluoro-5-methoxybenzoate; 159768-50-0; MFCD30132615
EINECS	Contact for details

Quality Control

Our Methyl 4-Fluoro-5-Methoxy-2-Nitrobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and rigorous control of residual solvents and impurities. We provide a Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.