Description

3-(4-Fluorophenyl)-4-Isoxazolecarboxylic Acid Ethyl Ester is a high-purity fluorinated isoxazole derivative, a key synthetic intermediate valued for its structural versatility in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring a reliable, high-quality building block to construct complex molecules with precision. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials, serving the needs of the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated isoxazole scaffold.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of complex heterocyclic compounds and fine chemicals in R&D laboratories.
• Material Science: Potential intermediate in the synthesis of specialty polymers, liquid crystals, or organic electronic materials due to its aromatic and heterocyclic structure.

Basic Information

Product Name	3-(4-Fluorophenyl)-4-Isoxazolecarboxylic Acid Ethyl Ester
CAS No.	159693-06-8
Molecular Formula	C12H10FNO3
Molecular Weight	235.21 g/mol
Synonyms	Ethyl 3-(4-fluorophenyl)-1,2-oxazole-4-carboxylate; 4-Isoxazolecarboxylic acid, 3-(4-fluorophenyl)-, ethyl ester; 3-(p-Fluorophenyl)-4-isoxazolecarboxylic acid ethyl ester; Ethyl 3-(4-fluorophenyl)isoxazole-4-carboxylate; 159693-06-8; 3-(4-Fluorophenyl)-4-carbethoxyisoxazole; 4-Carbethoxy-3-(4-fluorophenyl)isoxazole
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-4-Isoxazolecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.