Description

3-(4-Nitro-Phenyl)-Isoxazole-5-Carboxylic Acid Ethyl Ester is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile molecular scaffold, which incorporates both an isoxazole ring and a nitro-substituted phenyl group, making it a critical precursor for the development of novel pharmacologically active compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new chemical entities, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for compounds targeting inflammation, CNS disorders, or infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, or insecticides, leveraging the bioactive isoxazole and nitroaromatic motifs.
• Chemical Research & Development: Employed as a versatile building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, such as ligands for catalysts or components for specialty polymers.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-(4-Nitro-Phenyl)-Isoxazole-5-Carboxylic Acid Ethyl Ester
CAS No.	159670-70-9
Molecular Formula	C12H10N2O5
Molecular Weight	262.22 g/mol
Synonyms	Ethyl 3-(4-Nitrophenyl)isoxazole-5-carboxylate; 5-Isoxazolecarboxylic acid, 3-(4-nitrophenyl)-, ethyl ester; Ethyl 3-(p-Nitrophenyl)-1,2-oxazole-5-carboxylate; 3-(4-Nitrophenyl)-5-carbethoxyisoxazole; 3-(p-Nitrophenyl)isoxazole-5-carboxylic acid ethyl ester; 159670-70-9; 3-(4-Nitrophenyl)isoxazole-5-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 3-(4-Nitro-Phenyl)-Isoxazole-5-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.