Description

2H-Pyran-3-Carboxylicacid,Tetrahydro-,Methylester,(-)-(9Ci) is a chiral, non-racemic organic compound belonging to the class of tetrahydro-2H-pyran-3-carboxylate esters, serving as a valuable synthetic building block. This compound matters for its role as a key chiral intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors where stereochemical purity is critical. It is needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), fine chemicals, and advanced material precursors. The product is supplied under strict quality control to ensure batch-to-batch consistency for demanding synthetic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system or infectious diseases.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the specific stereochemistry influences biological activity.
• Fine Chemical Production: Serves as a versatile building block for creating complex, high-value specialty chemicals used in catalysis and material science.
• Academic & Industrial Research: Employed in methodological development and scale-up studies for new synthetic routes requiring enantiomerically pure components.
• Ligand and Catalyst Preparation: Acts as a precursor for the synthesis of chiral ligands and organocatalysts used in asymmetric transformations.
• Flavor and Fragrance Industry: Potential use as an intermediate for synthesizing specific chiral odorants or flavor compounds.

Basic Information

Product Name	2H-Pyran-3-Carboxylicacid,Tetrahydro-,Methylester,(-)-(9Ci)
CAS No.	159358-48-2
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(-)-Methyl tetrahydro-2H-pyran-3-carboxylate; (3R)-Tetrahydro-2H-pyran-3-carboxylic acid methyl ester; Methyl (3R)-oxane-3-carboxylate; Methyl (R)-tetrahydro-2H-pyran-3-carboxylate; Tetrahydro-2H-pyran-3-carboxylic acid, methyl ester, (-)-; L-159358-48-2; (R)-Methyl tetrahydro-2H-pyran-3-carboxylate
EINECS	Contact for details

Quality Control

Our 2H-Pyran-3-Carboxylicacid,Tetrahydro-,Methylester,(-)-(9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.