Description

1,4-Dioxaspiro[4.4]Nonane-7-Carbonitrile is a high-value, specialized organic building block featuring a spirocyclic acetal structure fused with a nitrile functional group. This unique molecular architecture makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and advanced material chemists for constructing novel compounds, including potential active ingredients and functional polymers. Its precise structure offers significant utility in medicinal chemistry for creating constrained analogs and exploring new chemical space.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in creating spirocyclic and conformationally restricted drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the spirocyclic moiety can enhance biological activity and stability.
• Advanced Material Precursor: Serves as a monomer or building block for specialty polymers, resins, and functional materials with tailored properties.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D for constructing complex heterocycles and natural product analogs.
• Ligand and Catalyst Development: Utilized in the synthesis of novel chiral ligands or organocatalysts for asymmetric synthesis applications.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value, low-volume specialty chemicals for various technological applications.

Basic Information

Product Name	1,4-Dioxaspiro[4.4]Nonane-7-Carbonitrile
CAS No.	159329-38-1
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	7-Cyano-1,4-dioxaspiro[4.4]nonane; 1,4-Dioxaspiro[4.4]nonane-7-carbonitrile; 7-Cyano-1,4-dioxaspiro[4.4]nonane; Spiro[1,3-dioxolane-2,1'-cyclopentane]-4-carbonitrile; 4-Cyano-1,5-dioxaspiro[5.4]decane (alternative numbering); 1,4-Dioxaspiro(4.4)nonane-7-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 1,4-Dioxaspiro[4.4]Nonane-7-Carbonitrile adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and synthesis applications. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support custom synthesis and can tailor specifications to meet specific project requirements under cGMP or ISO 9001 frameworks as needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.