Description

Trimethyl((4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Ethynyl)Silane is a highly versatile organoboron and organosilicon reagent, crucial for advanced synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation, specifically through Sonogashira and Suzuki-Miyaura cross-coupling reactions, which are fundamental to modern pharmaceutical and materials science research. This compound is essential for R&D chemists and process development scientists working in pharmaceutical intermediates, agrochemicals, and organic electronic materials. The CAS number for this compound is provided in the basic information table below.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for creating complex molecular architectures via palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of novel active ingredients requiring the introduction of alkynyl and boronate ester functionalities.
• Materials Science & OLED Development: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and semiconductors.
• Polymer Chemistry: Enables the functionalization of polymer backbones with specific side chains to tailor material properties.
• Chemical Biology & Bioconjugation: Utilized as a probe or linker for labeling biomolecules due to its reactive ethynyl and protected boronate groups.
• Academic & Industrial R&D: A fundamental reagent for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Item	Details
Product Name	Trimethyl((4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Ethynyl)Silane
CAS No.	159087-46-4
Molecular Formula	C13H25BO2Si
Molecular Weight	252.24 g/mol
Synonyms	2-(Trimethylsilylethynyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)ethynyltrimethylsilane; Ethynyltrimethylsilane, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl)-; Trimethyl(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethynyl)silane; Pinacol (Trimethylsilylethynyl)boronate
EINECS	Contact for details

Quality Control

Our Trimethyl((4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Ethynyl)Silane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including NMR, HPLC, and GC analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is between 2°C and 8°C. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress and oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.