Description

5,7-Dihydro-4H-Spiro[Benzo[D]Thiazole-6,2'-[1,3]Dioxolan]-2-Amine is a specialized spirocyclic organic compound featuring a benzothiazole core fused with a dioxolane ring. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for heterocyclic chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. The compound's structure offers significant potential for creating molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or metabolic conditions.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, or insecticides with potential novel modes of action.
• Organic Synthesis Building Block: Used in academic and industrial research to construct complex spirocyclic and fused heterocyclic systems for material science or chemical biology.
• Ligand and Catalyst Development: The amine and heterocyclic nitrogen atoms can be functionalized to create novel ligands for metal catalysis or molecular recognition.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized heterocyclic dyes due to the benzothiazole moiety.

Basic Information

Product Name	5,7-Dihydro-4H-Spiro[Benzo[D]Thiazole-6,2'-[1,3]Dioxolan]-2-Amine
CAS No.	159015-33-5
Molecular Formula	C10H10N2O2S
Molecular Weight	222.26 g/mol
Synonyms	2-Amino-5,7-dihydro-4H-spiro[benzo[d]thiazole-6,2'-[1,3]dioxolane]; Spiro[benzo[d]thiazole-6,2'-[1,3]dioxolan]-2-amine, 5,7-dihydro-4H-; 159015-33-5; 4H-Spiro[benzo[d]thiazole-6,2'-[1,3]dioxolan]-2-amine, 5,7-dihydro-; Benzothiazole, 2-amino-5,7-dihydro-4H-spiro[6,2'-[1,3]dioxolane]-; Spirocyclic benzothiazole-2-amine dioxolane
EINECS	Contact for details

Quality Control

Our production of 5,7-Dihydro-4H-Spiro[Benzo[D]Thiazole-6,2'-[1,3]Dioxolan]-2-Amine adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against established internal specifications using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.