Description

Benzhydrylaminoacetic Acid tert-Butyl Ester is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile intermediate for constructing complex peptide and small molecule libraries, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries who require reliable, high-quality intermediates for drug discovery and process scale-up.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected glycine derivative with a benzhydryl (BHA) backbone amide linker precursor.
• Combinatorial Chemistry: Serves as a versatile scaffold for generating diverse chemical libraries for high-throughput screening in drug discovery.
• Agrochemical Research: Intermediate in the development of new crop protection agents and herbicides.
• Chemical Biology Probes: Utilized in the design and synthesis of labeled compounds and molecular probes for biological target identification.
• Process Chemistry: Employed in the development and optimization of scalable synthetic routes for commercial manufacturing.

Basic Information

Product Name	Benzhydrylaminoacetic Acid tert-Butyl Ester
CAS No.	158980-46-2
Molecular Formula	C19H23NO3
Molecular Weight	313.39 g/mol
Synonyms	N-(Diphenylmethyl)glycine tert-Butyl Ester; tert-Butyl N-(Diphenylmethyl)glycinate; BHA-Gly-OtBu; (tert-Butoxycarbonylmethyl)(diphenylmethyl)amine; Glycine, N-(diphenylmethyl)-, 1,1-dimethylethyl ester; Benzhydrylglycine tert-Butyl Ester; 2-[(Diphenylmethyl)amino]acetic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our Benzhydrylaminoacetic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to current industry best practices, and specifications can be aligned with customer requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.