Description

Methyl 2-(Benzyloxycarbonylamino)Acetate is a protected amino acid derivative, specifically the methyl ester of N-Cbz-glycine, serving as a crucial building block in organic synthesis. This compound is valued for its role in facilitating peptide coupling reactions while protecting the amine functionality from unwanted side reactions. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex peptide-based drugs and therapeutic agents.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate glycine residues with a protected amine group.
• Bioconjugation: Serves as a starting material for creating linkers and modifiers used in antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Research: Employed in the design and synthesis of enzyme inhibitors, probes, and other bioactive molecules for mechanistic studies.
• Custom Synthesis: A fundamental reagent for contract research and manufacturing organizations (CROs/CMOs) producing custom organic compounds.
• Academic Research: Utilized in university laboratories for teaching advanced organic synthesis techniques and exploring new synthetic methodologies.

Basic Information

Product Name	Methyl 2-(Benzyloxycarbonylamino)Acetate
CAS No.	158457-27-3
Molecular Formula	C11H13NO4
Molecular Weight	223.23 g/mol
Synonyms	N-Carbobenzoxyglycine Methyl Ester; N-Cbz-Glycine Methyl Ester; Methyl N-Cbz-glycinate; Methyl (benzyloxycarbonylamino)acetate; Z-Gly-OMe; Benzyl N-(methoxycarbonylmethyl)carbamate; Glycine, N-[(phenylmethoxy)carbonyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-(Benzyloxycarbonylamino)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	<10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.