Description

3-(2-Bromo-1-Oxopropyl)-Spiro[2H-1,3-Benzoxazine-2,1'-Cyclohexan]-4(3H)-One is a specialized spirocyclic benzoxazine derivative with a reactive bromoacetyl functional group. This compound matters as a versatile and valuable chemical building block for synthesizing complex heterocyclic frameworks and advanced pharmaceutical intermediates. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with spirocyclic architectures.
• Organic Synthesis Building Block: The reactive bromoacetyl moiety allows for further functionalization, making it valuable for constructing complex molecular libraries.
• Material Science Research: Potential monomer or cross-linking agent in the development of advanced polymers with specific thermal or optical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Item	Detail
Product Name	3-(2-Bromo-1-Oxopropyl)-Spiro[2H-1,3-Benzoxazine-2,1'-Cyclohexan]-4(3H)-One
CAS No.	158299-05-9
Molecular Formula	C17H20BrNO3
Molecular Weight	366.25 g/mol
Synonyms	3-(2-Bromoacetyl)-Spiro[2H-1,3-benzoxazine-2,1'-cyclohexan]-4(3H)-one; 3-(2-Bromo-1-oxoethyl)-Spiro[2H-1,3-benzoxazine-2,1'-cyclohexan]-4(3H)-one; 2-Bromo-1-(4-oxo-1'-azaspiro[cyclohexane-1,2'-[2H][1,3]benzoxazin]-3'(4'H)-yl)ethan-1-one; Spiro[cyclohexane-1,2'-[2H][1,3]benzoxazine]-3'(4'H)-one, 3'-(2-bromoacetyl)-; 158299-05-9
EINECS	Contact for details

Quality Control

Our 3-(2-Bromo-1-Oxopropyl)-Spiro[2H-1,3-Benzoxazine-2,1'-Cyclohexan]-4(3H)-One is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.