Description

3-Naphthalen-2-Yl-3-Oxo-Propionic Acid Methyl Ester is a high-purity organic ester building block of significant interest in advanced chemical synthesis. This compound matters for its role as a versatile intermediate in the production of complex molecules, offering a reactive β-ketoester moiety attached to a naphthalene scaffold. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in display and lighting technologies.
• Dye and Pigment Intermediate: Employed in the synthesis of advanced colorants and fluorescent markers.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry, including cross-coupling and condensation reactions.
• Polymer Chemistry: Can be utilized to introduce naphthalene-based chromophores or functional groups into polymer backbones for specialty plastics.

Basic Information

Product Name	3-Naphthalen-2-Yl-3-Oxo-Propionic Acid Methyl Ester
CAS No.	158053-33-9
Molecular Formula	C₁₄H₁₂O₃
Molecular Weight	228.24 g/mol
Synonyms	Methyl 3-(naphthalen-2-yl)-3-oxopropanoate; 3-Oxo-3-(2-naphthyl)propionic acid methyl ester; 2-Naphthyl β-ketopropionate methyl ester; 3-(2-Naphthyl)-3-oxopropanoic acid methyl ester; Methyl 3-oxo-3-(naphthalen-2-yl)propanoate; β-Oxo-β-(2-naphthyl)propionic acid methyl ester; 158053-33-9; 3-(2-Naphthoyl)propionic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Naphthalen-2-Yl-3-Oxo-Propionic Acid Methyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.