Description

2-Aziridinecarboxylicacid,3-(1-Methylethyl)-,Methylester,(2S,3S)-(9Ci) CAS NO 158009-42-8 is a high-purity, stereochemically defined aziridine derivative, a crucial chiral building block in advanced organic synthesis. Its value lies in providing a constrained, three-membered heterocyclic ring system that enables the stereoselective introduction of functionalized amine groups into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals where precise stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including protease inhibitors, enzyme modulators, and other biologically active molecules.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where specific stereochemistry influences biological activity and environmental profile.
• Asymmetric Synthesis: Serves as a versatile electrophile or nucleophile in stereocontrolled ring-opening reactions to construct complex amino acids, amino alcohols, and other nitrogen-containing compounds.
• Ligand and Catalyst Development: Employed as a precursor for creating novel chiral ligands and organocatalysts used in enantioselective transformations.
• Polymer Science: Potential monomer for the synthesis of specialized polyamines or polymers with unique structural properties.
• Chemical Biology & Proteomics: Useful as a reactive handle for bioconjugation or as a scaffold in probe and inhibitor design for studying biological systems.

Basic Information

Item	Details
Product Name	2-Aziridinecarboxylicacid,3-(1-Methylethyl)-,Methylester,(2S,3S)-(9Ci)
CAS No.	158009-42-8
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(2S,3S)-3-Isopropylaziridine-2-carboxylic acid methyl ester; Methyl (2S,3S)-3-isopropylaziridine-2-carboxylate; (2S,3S)-Methyl 3-(propan-2-yl)aziridine-2-carboxylate; L-isopropylaziridine-2-carboxylic acid methyl ester; Aziridine-2-carboxylic acid, 3-(1-methylethyl)-, methyl ester, (2S,3S)-; (2S,3S)-3-(1-Methylethyl)-2-aziridinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of our (2S,3S)-3-Isopropylaziridine-2-carboxylic acid methyl ester is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, chiral analysis, and NMR to ensure identity, purity, and enantiomeric excess meet the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive aziridine ring, handle and store away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.