Description

Methyl 2-(1H-Indol-4-Yloxy)Acetate is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a versatile synthon in the development of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the synthesis of novel compounds targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with indole-based scaffolds targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and plant growth regulators that leverage the indole moiety's biological activity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex molecules in custom synthesis and process development for specialty chemicals.
• Biochemical Research: Employed in academic and industrial R&D for studying enzyme inhibition, receptor binding, and other structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors, dyes, and photostable materials due to its conjugated indole system.

Basic Information

Product Name	Methyl 2-(1H-Indol-4-Yloxy)Acetate
CAS No.	157889-30-0
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	Methyl (1H-indol-4-yloxy)acetate; Acetic acid, 2-(1H-indol-4-yloxy)-, methyl ester; 4-(Methoxycarbonylmethoxy)indole; Methyl (indol-4-yloxy)acetate; 1H-Indole-4-ol, acetate (ester); Methyl 2-(4-indolyloxy)acetate; Methyl 2-(4-hydroxyindol-1-yl)acetate (tautomeric form); 157889-30-0
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(1H-Indol-4-Yloxy)Acetate adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for identity confirmation and impurity profiling. Certificates of Analysis (COA) detailing purity, assay, and related substances are provided with each shipment and are available upon request to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.