Description

(2R,4S,5R)-3-Benzoyl-2-(4-Methoxyphenyl)-4-Phenyl-5-Oxazolidinecarboxylic Acid is a high-purity, stereochemically defined oxazolidine derivative that serves as a critical chiral building block and synthetic intermediate. Its precise stereochemistry is essential for imparting specific biological activity and directing the synthesis of complex, enantiomerically pure molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective therapeutics.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry can enhance efficacy and reduce environmental impact.
• Catalyst & Ligand Synthesis: Serves as a precursor for the preparation of novel chiral catalysts and ligands used in asymmetric catalysis.
• Academic & Process Chemistry: Employed in methodological research for constructing complex heterocycles and studying stereoselective reactions.
• Custom Synthesis & Scale-Up: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing custom intermediates for client projects.

Basic Information

Product Name	(2R,4S,5R)-3-Benzoyl-2-(4-Methoxyphenyl)-4-Phenyl-5-Oxazolidinecarboxylic Acid
CAS No.	157826-10-3
Molecular Formula	C24H19NO5
Molecular Weight	401.41 g/mol
Synonyms	5-Oxazolidinecarboxylic acid, 3-benzoyl-2-(4-methoxyphenyl)-4-phenyl-, (2R,4S,5R)-; (2R,4S,5R)-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-5-carboxylic acid; (2R,4S,5R)-2-(4-Methoxyphenyl)-4-phenyl-3-(phenylcarbonyl)-5-oxazolidinecarboxylic acid; Chiral oxazolidine carboxylic acid derivative; Benzoyloxazolidine carboxylic acid intermediate.
EINECS	Contact for details

Quality Control

Every batch of (2R,4S,5R)-3-Benzoyl-2-(4-Methoxyphenyl)-4-Phenyl-5-Oxazolidinecarboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and should be handled under inert atmosphere for long-term storage stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.