Description

Ethyl 3-Oxo-3-(2,3,4-Trifluorophenyl)Propanoate is a high-value fluorinated organic intermediate, specifically an ethyl ester of a β-keto acid derivative. This compound is critical for its role as a versatile building block in the synthesis of complex molecules, particularly in the pharmaceutical sector. It is primarily sought after by research and development teams and process chemists in the fine chemical and active pharmaceutical ingredient (API) manufacturing industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluorophenyl moiety enhances biological activity and stability.
• Material Science Research: Serves as a monomer or building block for creating specialty polymers and advanced organic materials with unique properties.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on introducing fluorine atoms into target molecules to modulate their physicochemical properties.

Basic Information

Product Name	Ethyl 3-Oxo-3-(2,3,4-Trifluorophenyl)Propanoate
CAS No.	157766-27-3
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	Ethyl 3-(2,3,4-Trifluorophenyl)-3-oxopropanoate; 3-Oxo-3-(2,3,4-trifluorophenyl)propanoic Acid Ethyl Ester; Ethyl 2,3,4-Trifluorobenzoylacetate; 2,3,4-Trifluorobenzoylacetic Acid Ethyl Ester; 157766-27-3; Ethyl β-Keto-2,3,4-trifluorophenylpropionate; Acetic acid, 2,3,4-trifluorobenzoyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Oxo-3-(2,3,4-Trifluorophenyl)Propanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.