Description

2,4,6-Trichlorophenylisocyanide is a versatile and highly reactive organic building block characterized by its isocyanide functional group and halogenated aromatic ring. This compound is valued for its role as a key precursor in the synthesis of complex heterocycles and functional materials, enabling efficient carbon-carbon and carbon-heteroatom bond formation. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for constructing nitrogen-containing heterocyclic scaffolds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create new bioactive molecules.
• Ligand Synthesis: Acts as a precursor for the preparation of specialized isocyanide-based ligands used in coordination chemistry and catalysis.
• Material Science: Employed in the research and development of functional polymers, dyes, and photoactive materials.
• Multicomponent Reactions (MCRs): A valuable reactant in Passerini and Ugi-type reactions for the efficient, one-pot generation of compound libraries for drug discovery.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and enzyme activity.

Basic Information

Item	Detail
Product Name	2,4,6-Trichlorophenylisocyanide
CAS No.	157766-10-4
Molecular Formula	C7H2Cl3N
Molecular Weight	210.46 g/mol
Synonyms	2,4,6-Trichlorophenyl isocyanide; 2,4,6-Trichlorophenyl isonitrile; 1-Isocyano-2,4,6-trichlorobenzene; Isocyanic acid, 2,4,6-trichlorophenyl ester; 2,4,6-Trichlorobenzene isocyanide; 2,4,6-Trichlorophenyl iso-cyanide; (2,4,6-Trichlorophenyl)isocyanide
EINECS	Contact for details

Quality Control

Every batch of 2,4,6-Trichlorophenylisocyanide is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent evaporation and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.