Description

(S)-3-Azido-4,4-Dimethyldihydrofuran-2(3H)-One is a high-value chiral building block and azide synthon, essential for advanced organic synthesis. Its core value lies in enabling the stereoselective construction of complex molecules, particularly through click chemistry and other azide-based transformations. This compound is critically needed by pharmaceutical R&D teams and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and novel materials. We supply this specialty intermediate with a focus on high purity and batch-to-batch consistency to support your most demanding synthetic routes.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Click Chemistry Reagent: Serves as a vital azide component for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create triazole linkages.
• Agrochemical Synthesis: Used in the research and development of advanced, stereospecific pesticides and herbicides.
• Material Science: Building block for creating functional polymers and smart materials with specific stereochemical properties.
• Academic & Industrial R&D: Essential tool for medicinal chemistry, process chemistry, and methodology development in organic synthesis.
• Peptidomimetics & Bioconjugation: Facilitates the introduction of azide functional groups into peptides and biomolecules for labeling and conjugation.

Basic Information

Product Name	(S)-3-Azido-4,4-Dimethyldihydrofuran-2(3H)-One
CAS No.	157717-58-3
Molecular Formula	C6H9N3O2
Molecular Weight	155.16 g/mol
Synonyms	(3S)-3-Azido-4,4-dimethyl-2-oxotetrahydrofuran; (S)-3-Azido-4,4-dimethylbutyrolactone; (S)-4,4-Dimethyl-3-azidodihydro-2(3H)-furanone; 3-Azido-4,4-dimethyl-dihydrofuran-2(3H)-one, (S)-; (S)-3-Azido-4,4-dimethyl-dihydrofuran-2(3H)-one; Azido-dimethyl-dihydrofuranone
EINECS	Contact for details

Quality Control

Our (S)-3-Azido-4,4-Dimethyldihydrofuran-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting R&D and production standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.