Description

2-Formyl-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a versatile and high-purity chemical intermediate, essential for advanced organic synthesis. Its value lies in its protected amine and aldehyde functionalities, which enable precise and efficient construction of complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of piperidine-based drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides that require complex heterocyclic scaffolds.
• Peptidomimetics & PROTACs: Serves as a crucial precursor in the design and synthesis of peptide mimics and proteolysis-targeting chimeras (PROTACs) for targeted protein degradation.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands and organocatalysts for asymmetric synthesis and metal complexation.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing high-value specialty chemicals.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	2-Formyl-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	157634-02-1
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	1-Boc-2-formylpiperidine; 1-(tert-Butoxycarbonyl)-2-formylpiperidine; 2-Formyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 2-formylpiperidine-1-carboxylate; N-Boc-2-formylpiperidine; 2-Formylpiperidine-1-carboxylic acid tert-butyl ester; 1-N-Boc-2-piperidinecarboxaldehyde; Boc-2-formylpiperidine
EINECS	Contact for details

Quality Control

Our 2-Formyl-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent performance for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.