Description

2-Pyridinecarboxylicacid,3-Amino-,Trimethylsilylester(9Ci) CAS NO 157562-24-8 is a specialized organosilicon derivative of 3-aminopicolinic acid, serving as a key protected intermediate in advanced organic synthesis. This compound is valued for its role in introducing the 3-amino-2-pyridinecarboxylate moiety under mild conditions, enabling the construction of complex heterocyclic frameworks. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of drug candidates, particularly those targeting neurological disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand Precursor: Serves as a starting material for the preparation of sophisticated chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Research: Employed in the design and synthesis of peptide analogs where the pyridine ring mimics natural amino acid side chains.
• Material Science: Acts as a functional monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological pathways and enzyme mechanisms.

Basic Information

Product Name	2-Pyridinecarboxylicacid,3-Amino-,Trimethylsilylester(9Ci)
CAS No.	157562-24-8
Molecular Formula	C9H14N2O2Si
Molecular Weight	210.31 g/mol
Synonyms	3-Amino-2-pyridinecarboxylic acid trimethylsilyl ester; Trimethylsilyl 3-aminopicolinate; 3-Aminopicolinic Acid Trimethylsilyl Ester; 3-Amino-2-(trimethylsilyloxycarbonyl)pyridine; 2-(Trimethylsiloxycarbonyl)-3-aminopyridine; TMS 3-aminopicolinate; (3-Aminopyridin-2-yl)carboxylic acid trimethylsilyl ester
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxylicacid,3-Amino-,Trimethylsilylester(9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.