Description

Carbamic Acid, [(1S,2S)-2-Hydroxy-1-Methylpropyl]-, 1,1-Dimethylethyl Ester is a high-purity, chiral intermediate of significant importance in asymmetric synthesis. This compound is valued for its role as a key building block in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where stereochemical control is paramount. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the production of enantiomerically pure compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
• Catalyst Ligand Precursor: Serves as a starting material for the preparation of sophisticated chiral ligands used in asymmetric catalysis.
• Peptidomimetics Research: Employed in medicinal chemistry for constructing peptide analogs and protease inhibitors.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring specific stereochemistry for advanced material applications.

Basic Information

Product Name	Carbamic Acid, [(1S,2S)-2-Hydroxy-1-Methylpropyl]-, 1,1-Dimethylethyl Ester
CAS No.	157394-45-1
Molecular Formula	C9H19NO3
Molecular Weight	189.25 g/mol
Synonyms	(1S,2S)-1,2-Dimethyl-3-[(tert-butoxycarbonyl)amino]propan-1-ol; tert-Butyl N-[(1S,2S)-2-Hydroxy-1-methylpropyl]carbamate; (1S,2S)-2-((tert-Butoxycarbonyl)amino)-1-methylpropan-1-ol; Boc-L-threoninol; (2S,3S)-3-Amino-2-methyl-1-propanol N-Boc derivative; tert-Butyl (1S,2S)-2-hydroxy-1-methylpropylcarbamate; N-Boc-L-threoninol
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(1S,2S)-2-Hydroxy-1-Methylpropyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.