Description

4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridine Dihydrochloride is a high-purity heterocyclic building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its versatile pyrazolopyridine core, which is a privileged scaffold in medicinal chemistry for designing bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the central nervous system (CNS) and oncology spaces. CAS number 157327-44-1.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• CNS Drug Development: Employed in the research and synthesis of potential therapeutics for neurological and psychiatric disorders.
• Kinase Inhibitor Synthesis: Serves as a precursor in the creation of kinase inhibitors, a major class of drugs for cancer and inflammatory diseases.
• Chemical Biology Probes: Utilized to develop tool compounds for studying biological processes and target validation.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.

Basic Information

Product Name	4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridine Dihydrochloride
CAS No.	157327-44-1
Molecular Formula	C6H12Cl2N3
Molecular Weight	197.09 g/mol
Synonyms	1H-Pyrazolo[4,3-c]pyridine, 4,5,6,7-tetrahydro-, dihydrochloride; 4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine hydrochloride (1:2); 4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine dihydrochloride; Pyrazolo[4,3-c]pyridine, 4,5,6,7-tetrahydro-1H-, dihydrochloride; 157327-44-1; 4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine HCl; 1,2,3,4-Tetrahydropyrazolo[4,3-c]pyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.