Description

Ethyl 4-(((tert-Butoxycarbonyl)Amino)Methyl)Benzoate is a high-purity, protected amino acid derivative widely used as a critical building block in organic synthesis. This compound is essential for researchers and manufacturers requiring a versatile intermediate with a reactive amine group protected by the acid-labile Boc group. It is primarily utilized in the pharmaceutical and biotechnology sectors for the synthesis of peptides, active pharmaceutical ingredients (APIs), and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide chemistry to incorporate a protected benzylamine moiety.
• Protecting Group Chemistry: Serves as a reagent where the tert-butoxycarbonyl (Boc) group protects an amine functionality during multi-step syntheses.
• Bioconjugation: Employed in the development of linker molecules for antibody-drug conjugates (ADCs) and other bioconjugates.
• Organic Synthesis: A versatile intermediate for constructing complex aromatic compounds and fine chemicals.
• Research & Development: Used in academic and industrial R&D labs for medicinal chemistry and chemical biology studies.

Basic Information

Product Name	Ethyl 4-(((tert-Butoxycarbonyl)Amino)Methyl)Benzoate
CAS No.	157311-42-7
Molecular Formula	C16H23NO4
Molecular Weight	293.36 g/mol
Synonyms	Ethyl 4-((Boc-amino)methyl)benzoate; 4-((((tert-Butoxy)carbonyl)amino)methyl)benzoic acid ethyl ester; Benzoic acid, 4-(((1,1-dimethylethoxy)carbonyl)amino)methyl)-, ethyl ester; Ethyl p-((N-Boc-amino)methyl)benzoate; Boc-AMB-OEt; N-Boc-4-(aminomethyl)benzoic acid ethyl ester; N-(tert-Butoxycarbonyl)-4-(aminomethyl)benzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-(((tert-Butoxycarbonyl)Amino)Methyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.