Description

α-D-Erythro-Pentofuranous-2-Ulose 1,3,5-Tribenzoate is a high-purity, advanced pharmaceutical intermediate and chiral building block. This compound is critical for the synthesis of complex nucleoside analogs and carbohydrate-based therapeutics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in antiviral drug development, oligonucleotide synthesis, and medicinal chemistry research.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer applications.
• Oligonucleotide Synthesis: Serves as a protected sugar moiety for the construction of modified DNA/RNA strands in antisense and siRNA therapeutic development.
• Medicinal Chemistry Research: Used as a sophisticated building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Carbohydrate Chemistry: Essential reagent for studying glycosylation reactions and synthesizing complex, biologically active oligosaccharides.
• Process Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) requiring specific pentofuranose frameworks.

Basic Information

Product Name	α-D-Erythro-Pentofuranous-2-Ulose 1,3,5-Tribenzoate
CAS No.	157037-56-4
Molecular Formula	C26H22O8
Molecular Weight	462.45 g/mol
Synonyms	1,3,5-Tri-O-benzoyl-α-D-erythro-pentofuranos-2-ulose; 1,3,5-Tri-O-benzoyl-α-D-ribo-pentofuranos-2-ulose; 2-Keto-1,3,5-tri-O-benzoyl-α-D-ribofuranose; Tribenzoyl-α-D-ribo-pentofuranos-2-ulose; α-D-erythro-Pentofuranos-2-ulose 1,3,5-tribenzoate
EINECS	Contact for details

Quality Control

Our α-D-Erythro-Pentofuranous-2-Ulose 1,3,5-Tribenzoate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.