Description

Methyl 2-(2-{[(9H-Fluoren-9-Yl)Methoxy]Carbonylamino}Ethylamino)Acetate is a specialized Fmoc-protected amino acid derivative, a critical building block in modern peptide synthesis. Its primary value lies in enabling the controlled, sequential assembly of complex peptides with high purity and yield. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of specific amino acid sequences, particularly useful for introducing glycine derivatives or spacer units.
• Pharmaceutical Research & Development: Serves as a crucial raw material in the R&D of peptide-based drugs, including hormone analogs, antimicrobial peptides, and targeted therapeutics.
• Bioconjugation and Linker Chemistry: Used to create peptide-drug conjugates (PDCs) or to attach peptides to surfaces, nanoparticles, or other biomolecules for diagnostic and therapeutic applications.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening to identify new bioactive compounds.
• Academic & Institutional Research: Fundamental reagent for studying peptide structure, function, and interactions in biochemistry and molecular biology laboratories.
• Production of Custom Peptides: Used by CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) for the reliable, scalable production of custom peptide sequences for clients.

Basic Information

Product Name	Methyl 2-(2-{[(9H-Fluoren-9-Yl)Methoxy]Carbonylamino}Ethylamino)Acetate
CAS No.	156939-69-4
Molecular Formula	C21H24N2O5
Molecular Weight	384.43 g/mol
Synonyms	Fmoc-N-amido-PEG2-acid methyl ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N'-(methoxycarbonylmethyl)ethylenediamine; Methyl N-(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}ethyl)glycinate; Fmoc-NH-PEG2-CH2-COOMe; (2-{[(Fmoc)amino]ethyl}amino)acetic acid methyl ester; Nα-Fmoc-Nβ-(methoxycarbonylmethyl)-1,2-diaminoethane; N-(2-Fmocaminoethyl)glycine methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-(2-{[(9H-Fluoren-9-Yl)Methoxy]Carbonylamino}Ethylamino)Acetate is manufactured under strict quality systems to ensure consistency and reliability for sensitive synthetic applications. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral purity checks where applicable. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.