Description

5-Tris(Hydroxymethyl)Methylamino-2-(3,6-Dihydroxy-9H-Xanthen-10-Yl)Benzoate is a high-purity chemical intermediate and reagent, primarily known for its role in the synthesis of advanced fluorescent probes and dyes. Its value lies in its ability to act as a key building block for creating sensitive and specific detection agents used in life science research and diagnostics. This compound is essential for manufacturers and research institutions developing fluorescent labeling kits, bioassays, and diagnostic reagents that require precise molecular conjugation.

Application

• Fluorescent Probe Synthesis: A critical precursor for manufacturing xanthene-based fluorescent dyes and molecular tags.
• Bio-conjugation Reagent: Used to label antibodies, proteins, and nucleic acids for fluorescence microscopy (e.g., FISH) and flow cytometry.
• Diagnostic Assay Development: Key component in the production of reagents for ELISA, lateral flow assays, and other clinical diagnostic tests.
• Cell Biology Research: Enables the creation of specific stains for cellular imaging and tracking intracellular processes.
• Chemical Biology: Serves as a versatile intermediate for designing novel sensor molecules and activity-based probes.
• Material Science: Potential use in developing fluorescent sensors and smart materials for environmental or industrial monitoring.

Basic Information

Product Name	5-Tris(Hydroxymethyl)Methylamino-2-(3,6-Dihydroxy-9H-Xanthen-10-Yl)Benzoate
CAS No.	156862-28-1
Molecular Formula	C26H25NO9
Molecular Weight	495.48 g/mol
Synonyms	5-TAMRA SE; 5-Carboxytetramethylrhodamine succinimidyl ester; 5-TAMRA, SE; 5-Carboxy-tetramethylrhodamine N-succinimidyl ester; 6-TAMRA SE isomer; Tetramethylrhodamine-5-isothiocyanate precursor; Xanthylium, 9-(2-(ethoxycarbonyl)phenyl)-3,6-bis((tris(hydroxymethyl)methyl)amino)-, inner salt; 5-TAMRA NHS Ester
EINECS	Contact for details

Quality Control

Our 5-Tris(Hydroxymethyl)Methylamino-2-(3,6-Dihydroxy-9H-Xanthen-10-Yl)Benzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Orange to red powder or crystalline solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.