Description

cis-4-Oxo-1,2-Cyclopentanedicarboxylic Acid Diethyl Ester is a high-purity, versatile diester derivative of a functionalized cyclopentanone, serving as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its value lies in the reactive ketone and ester functionalities within a constrained five-membered ring, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandin analogs, nucleoside derivatives, and other bioactive molecules with cyclopentane cores.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the cis-substituted cyclopentanone structure imparts specific biological activity.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and advanced materials requiring specific stereochemistry and functional group arrays.
• Academic & R&D: A valuable substrate in methodological development for asymmetric synthesis, ring-forming reactions, and catalysis studies.
• Ligand and Catalyst Development: The structure can be modified to create novel chiral ligands for asymmetric catalysis.

Basic Information

Product Name	cis-4-Oxo-1,2-Cyclopentanedicarboxylic Acid Diethyl Ester
CAS No.	156293-34-4
Molecular Formula	C12H18O5
Molecular Weight	242.27 g/mol
Synonyms	Diethyl cis-4-oxo-1,2-cyclopentanedicarboxylate; 4-Oxocyclopentane-1,2-dicarboxylic Acid Diethyl Ester; cis-1,2-Bis(ethoxycarbonyl)-4-cyclopentanone; 4-Oxo-cyclopentane-1,2-dicarboxylic acid diethyl ester; Ethyl 4-oxo-1,2-cyclopentanedicarboxylate; 156293-34-4; cis-Diethyl 4-oxocyclopentane-1,2-dicarboxylate
EINECS	Contact for details

Quality Control

Our cis-4-Oxo-1,2-Cyclopentanedicarboxylic Acid Diethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP and ISO compliant production for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.